What is Agmatine Sulfate
Agmatine is derived from L-arginine through decarboxylation (the removal of a carboxylic acid group). It is stored in neurons and is released during neuronal activation. Agmatine is considered to be a neurotransmitter and neuromodulator.
Preliminary research suggests agmatine has potential use in the treatment of neuropathic pain and drug addiction. It also protects the brain from toxins and strokes.
Though supplementing agmatine by itself can decrease the perception of pain, it works synergistically with painkillers like morphine and fentanyl. Agmatine's synergy with opioids allows it to reduce pain killer tolerance, the possibility of addiction, and pain itself.
Agmatine is currently under investigation as a possible anticancer compound, but the research is in its very early stages. These results only indicate that further studies should be conducted; future trials may find that agmatine is not effective at all against cancer in a living animal.
Agmatine prevented the growth of connective tissue tumors in mice. Agmatine also prevented the growth of intestinal tumor cells in a lab study by decreasing polyamine production. These are very early studies and more research will be needed before agmatine is recommended in cancer patients.
Agmatine has dual functions: A) selective inhibition of the enzyme that breaks down nitric oxide – the result, increased (no) nitric oxide. B) the direct stimulation of no. With increased no you create an environment for increased nutrient delivery, improved metabolic waste removal, and most importantly, increased overall performance.
What is Agmatine Sulfate Supplement Powder?
Agmatine is available as an oral supplement in powder form known as agmatine sulfate, which is effective at increasing agmatine levels in the body. Direct supplementation with agmatine sulfate is the only means of increasing agmatine that has been studied in humans.
Agmatine Sulfate Benefits and Uses
There is presently a great interest in the therapeutic potential of agmatine, decarboxylated arginine, for various diseases. Recent clinical studies have already shown that oral agmatine sulfate given for up to 3 weeks provides a safe and, as compared with current therapeutics, more effective treatment for neuropathic pain. These studies have ushered in the use of dietary agmatine as a nutraceutical.
Once known primarily as a supplement for bodybuilders, agmatine sulfate is gaining popularity among men and women of all ages and walks of life as a way to increase energy and enhancement mental and physical wellbeing.
As mentioned already Agmatine is a metabolite of the amino acid l-arginine, and like its parent compound, it boosts the body's production of nitric oxide, which can dilate blood vessels to facilitate blood flow to the muscles, brain, and other tissues.
In fact, agmatine is much more effective than l-arginine in enhancing nitric oxide levels, which is why it is fast becoming a favorite for endurance athletes and others looking for healthy ways to fight off fatigue and improve recovery time after exercise.
Agmatine Sulfate Promotes Cognitive Function
Agmatine is a compound naturally formed from the amino acid l-arginine. It is a neurotransmitter found predominantly in neurons. Because it is capable of targeting multiple receptors, researchers are investigating it in the context of a spectrum of complex diseases.
Some research suggests that agmatine may play a role in cognitive function, stress resiliency, mood, and athletic performance. The highest levels of agmatine are found in the gut, where it is produced by the microbes living there.
How to take Agmatine Sulfate and Agmatine Sulfate Dosage
There is presently a great interest in the therapeutic potential of agmatine, decarboxylated arginine, for various diseases. Recent clinical studies have already shown that oral agmatine sulfate given for up to 3 weeks provides a safe and, as compared with current therapeutics, more effective treatment for neuropathic pain.
These studies have ushered in the use of dietary agmatine as a nutraceutical. However, in view of information paucity, assessment of long-term safety of oral agmatine treatment is now clearly required.