By using lipopeptide, a lipid, and peptide the combination stops the SARS-CoV-2 from getting taken in right into the cell's membrane layer.
The SARS-CoV2 infection, like any other infection, used the cell's membrane to reproduce itself.
A lipopeptide in the spray ‘inserts itself right into the spike of a healthy protein, staying with the chains. This is area that would normally bind to a receptor and infect the cell.
Daily intranasal administration to ferrets completely prevented SARS-CoV-2 direct-contact transmission … during 24-hour co-housing with infected animals, under stringent conditions that resulted in infection of 100% of untreated animals
These lipopeptides are highly stable and non-toxic and thus readily translate into a safe and effective intranasal prophylactic approach to reduce transmission of SARS-CoV-2
The researchers examined 4 various variants of the infection, including both the well-known “Wuhan” and “Italian” strain of the virus.
These also included the coronaviruses SARS and MERS is in there research.
In the cell cultures, the lipoprotein protected all strains of the pandemic infection.